This PedsCases Note provides a one-page infographic on Tumor Lysis Syndrome (TLS). This is an oncologic emergency caused by the release of intracellular components when cancer cells break down. It was created by Michelle Choi (Medical Student, University of Alberta), with the help of Dr. Maria Spavor (Pediatric Oncologist, University of Alberta).  

Click on the image below for the full-screen PDF handout.

Related Content

• Podcast: Tumor Lysis Syndrome (TLS) in Pediatric Populations

• Note: Acute Lymphoblastic Leukemia

• Podcast: Approach to Acute Leukemia in Children

References

1. Adeyinka A, Kaur A, Bashir K. Tumor Lysis Syndrome. [Updated 2024 Oct 5]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK518985/

2. Thomas B. Russell, David E. Kram; Tumor Lysis Syndrome. Pediatr Rev January 2020; 41 (1): 20–26. https://doi-org.login.ezproxy.library.ualberta.ca/10.1542/pir.2018-0243

There are no conflicts of interest to disclose by the authors.