Pediatric Education Online

This PedsCases Note provides a one-page infographic on Alternating Hemiplegia of Childhood which is a rare neurological disorder marked by recurrent episodes of paralysis affecting each side of the body. It was created by Iman Kassam a medical student at the University of Alberta with the help of Dr. Colin Wilbur
Click on the image below for the full-screen PDF handout
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References:
Kansagra, S., Mikati, M. A., & Vigevano, F. (2013). Alternating hemiplegia of childhood. Handbook of clinical neurology, 112, 821–826. https://doi.org/10.1016/B978-0-444-52910-7.00001-5
Capuano A, Garone G, Tiralongo G, Graziola F. Alternating Hemiplegia of Childhood: Understanding the Genotype-Phenotype Relationship of ATP1A3 Variations. Appl Clin Genet. 2020 Mar 30;13:71-81. doi: 10.2147/TACG.S210325. PMID: 32280259; PMCID: PMC7125306.
Pavone, P., Pappalardo, X. G., Ruggieri, M., Falsaperla, R., & Parano, E. (2022). Alternating hemiplegia of childhood: a distinct clinical entity and ATP1A3-related disorders: A narrative review. Medicine, 101(31), e29413. https://doi.org/10.1097/MD.0000000000029413
Rosewich, H., Sweney, M. T., DeBrosse, S., Ess, K., Ozelius, L., Andermann, E., Andermann, F., Andrasco, G., Belgrade, A., Brashear, A., Ciccodicola, S., Egan, L., George, A. L., Jr, Lewelt, A., Magelby, J., Merida, M., Newcomb, T., Platt, V., Poncelin, D., Reyna, S., … Swoboda, K. (2017). Research conference summary from the 2014 International Task Force on ATP1A3-Related Disorders. Neurology. Genetics, 3(2), e139. https://doi.org/10.1212/NXG.0000000000000139
Masoud, M., Prange, L., Wuchich, J., Hunanyan, A., & Mikati, M. A. (2017). Diagnosis and Treatment of Alternating Hemiplegia of Childhood. Current treatment options in neurology, 19(2), 8. https://doi.org/10.1007/s11940-017-0444-7
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