This PedsCases note provides a one-page overview on hemoglobinopathies, including alpha-thalassemia, beta-thalassemia and sickle cell disease. It was created by Katie Pirie, a medical student at the Royal College of Surgeons in Ireland with the help of Dr. Roseann Andreou. 

Click the image below for a full-page PDF.

Related Content:

Podcast: Approach to a Patient with Sickle Cell Disease

Podcast: Approach to Thalassemia (Part 1)

Podcast: Approach to Thalassemia (Part 2)

References

1. Nelson M, Noisette L, Pugh N, Gordeuk V, Hsu LL, Wun T, et al. The clinical spectrum of HbSC sickle cell disease-not a benign condition. British Journal of Haematology. 2024;205(2):653–63. 

2. Needs T, Gonzalez-Mosquera LF, Lynch DT. Beta Thalassemia. In: StatPearls [Internet] [Internet]. StatPearls Publishing; 2023 [cited 2024 Sep 24]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK531481/

3. Husain A Sattar. Fundamentals of Pathology. united States of America: Pathoma LLC; 2023. 

4. Tom Lissauer, Will Carroll. Illustrated Textbook of Paediatrics. 6th ed. Elsevier Limited; 2022.