This PedsCases note provides a one-page summary of hand, foot and mouth disease, including its presentation, pathogenesis, transmission, diagnosis, management and prevention. It was created by Annabelle Wong, a medical student at the University of Calgary with help from Dr. Bonita Lee, a professor in the Division of Infectious Disease at the University of Alberta. 

Click the image below for a full-page PDF. 

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References

1. Canadian Paediatric Society. (2019, May). Hand, foot and mouth disease. Retrieved October 26, 2023, from Caring for Kids: https://caringforkids.cps.ca/handouts/health-conditions-and-treatments/hand_foot_and_mouth_disease

2. Centers for Disease Control and Prevention. (2023, May 11). Hand, Foot, and Mouth Disease (HFMD). Retrieved November 13, 2023, fromhttps://www.cdc.gov/hand-foot-mouth/index.html

3. DynaMed. (2023). Hand-foot-and-mouth Disease. Retrieved October 26, 2023, from EBSCO Information Services: https://www-dynamed-com.ezproxy.lib.ucalgary.ca/condition/hand-foot-and-mouth-disease

4. Healthwise Staff. (2022, October 31). Hand-Foot-and-Mouth Disease. Retrieved November 13, 2023, from MyHealth.Alberta.ca:https://myhealth.alberta.ca/Health/Pages/conditions.aspx?hwid=ty6230

5. Healthwise Staff. (2022, October 31). Hand-Foot-and-Mouth Disease in Children: Care Instructions. Retrieved November 13, 2023, from MyHealth.Alberta.ca: https://myhealth.alberta.ca/Health/aftercareinformation/pages/conditions.aspx?hwid=uh3650

6. Murren-Boezem, J. (2022, August). Hand, Foot, and Mouth Disease. Retrieved October 26, 2023, from Nemours® KidsHealth:https://kidshealth.org/en/parents/hfm.html?view=ptr

7. Romero, J. R. (2022, March 28). Hand, foot, and mouth disease and herpangina. Retrieved October 26, 2023, from UpToDate:https://www.uptodate.com/contents/hand-foot-and-mouth-disease-and-herpangina

8. Saguil, A., Kane, S. F., Lauters, R., & Mercado, M. G. (2019, October 1). Hand-Foot-and-Mouth Disease: Rapid Evidence Review. American Family Physician, 100(7), 408-414.

9. Shi, Y., Chen, P., Bai, Y., Xu, X., & Liu, Y. (2023). Seroprevalence of coxsackievirus A6 and enterovirus A71 infection in humans: a systematic review and meta-analysis. Archives of Virology, 37, 168. doi:https://doi.org/10.1007/s00705-022-05642-0

10. Yi, Z., Pei, S., Suo, W., Wang, X., Huang, Z., Yi, A., . . . Huang, X. (2022). Epidemiological characteristics, routine laboratory diagnosis, clinical signs and risk factors for hand, -foot -and -mouth disease: A systematic review and meta-analysis. PLoS One, 17(4), e0267716. doi:https://doi.org/10.1371/journal.pone.0267716